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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CEFIDEROCOL

CEFIDEROCOL


ATC J01DI04

ANTIINFECTIVES
CEPHALOSPORIN ANTIBACTERIAL
TREATMENT OF COMPLICATED URINARY TRACT INFECTIONS (CUTI)
BINDS TO EXTRACELLULAR FREE FERRIC IRON FOR A PASSIVE DIFFUSION VIA PORIN CHANNEL

INTRAVENOUS

Cmax 119.3 MICROMOLAR

VD 18 LITER

PPB 50 PERCENT

Cl 5.18 LITER / HOUR

HT 2.5 HOUR

PENICILLIN-BINDING PROTEINS (PBPS)

Peptidoglycan synthase FtsI UNIPROT P0AD68 ftsI -- Penicillin-binding protein 1A UNIPROT Q07806 mrcA

more at DrugCentral

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