Cheminformatic Tools and Databases for Pharmacology

session 84678 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
IVOSIDENIB

IVOSIDENIB


ATC L01XX62

ANTINEOPLASTIC
TARGETS MUTANT ISOCITRATE DEHYDROGENASE-1 (IDH1) IDH1 R132
INHIBITOR
TREATMENT OF ACUTE MYELOID LEUKEMIA (AML)

ORAL

Cmax 7.7 MICROMOLAR

Tmax 3 HOUR

VD 234 LITER

PPB 94 PERCENT

Cl 4.3 LITER / HOUR

HT 93 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN AQUEOUS SOLUTIONS BETWEEN PH 1.2 AND 7.4

ISOCITRATE DEHYDROGENASE-1 (IDH1)

Isocitrate dehydrogenase [NADP] cytoplasmic O75874ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |