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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PROCHLORPERAZINE
| PROCHLORPERAZINE | NERVOUS SYSTEM | ORAL INJECTION RECTAL | VD 1430 LITER (65 KILOGRAM) Cl 62.4 LITER / HOUR (65 KILOGRAM) HT 9 HOUR | D(2) DOPAMINE RECEPTOR PDB 3M0W (STRUCTURE OF S100A4 WITH PCP) LIGAND CODE = P77 (link to the list of PDB complexes) Download experimental 3D coordinates of P77 with added hydrogens | D(2) dopamine receptor UNIPROT P14416 DRD2 -- D(3) dopamine receptor UNIPROT P35462 DRD3 more at DrugCentral | EMA | |||
