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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BALOXAVIR (is an active metabolite)
| BALOXAVIR | ANTIINFECTIVES | - | Cmax 199 NANOMOLAR Tmax 4 HOUR VD 1180 LITER PPB 93.4 PERCENT Cl 10.3 LITER / HOUR HT 79.1 HOUR | POLYMERASE ACIDIC PROTEIN PDB 6FS6 (INFLUENZA A, CALIFORNIA 04 2009 (PH1N1) ENDONUCLEASE) LIGAND CODE = E4Z (link to the list of PDB complexes) Download experimental 3D coordinates of E4Z with added hydrogens | Polymerase acidic protein UNIPROT P03433 more at DrugCentral | EMA | |||
