Cheminformatic Tools and Databases for Pharmacology

session 99380 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TAFENOQUINE

TAFENOQUINE


ATC P01BA07

ANTIPARASITIC
ANTIMALARIAL
8-AMINOQUINOLINE
ACTIVE AGAINST ALL THE STAGES OF PLASMODIUM SPECIES
INHIBITS HEMATIN POLYMERIZATION AND INDUCES APOPTOTIC LIKE DEATH OF THE PARASITE

ORAL

Cmax 317 NANOMOLAR

Tmax 14 HOUR

VD 2470 LITER

PPB 99.5 PERCENT

Cl 4.2 LITER / HOUR

HT 396 HOUR

Unknown - more at DrugCentralANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |