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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SARECYCLINE
| SARECYCLINE | ANTIINFECTIVES | ORAL | Tmax 1.75 HOUR VD 94.2 LITER PPB 68.6 PERCENT Cl 3 LITER / HOUR HT 21.5 HOUR | PDB 6XQD (CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH SARECYCLINE, UUC-MRNA, AND DEACYLATED P-SITE TRNA AT 2.80A RESOLUTION) LIGAND CODE = V7A (link to the list of PDB complexes) Download experimental 3D coordinates of V7A with added hydrogens | Unknown more at DrugCentral | EMA | |||
