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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TRICLABENDAZOLE (has an active metabolite)
| TRICLABENDAZOLE | ANTIPARASITIC | ORAL | Cmax 1.16 MICROMOLAR Tmax 3.5 HOUR PPB 96.7 PERCENT HT 8 HOUR | PDB 7ERI (CRYSTAL STRUCTURE OF V30M-TTR IN COMPLEX WITH TRICLABENDAZOLE) LIGAND CODE = JA9 (link to the list of PDB complexes) Download experimental 3D coordinates of JA9 with added hydrogens | Unknown more at DrugCentral | EMA | |||
