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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
AVATROMBOPAG

AVATROMBOPAG


ATC B02BX08

BLOOD
THROMBOPOIETIN RECEPTOR AGONIST (TPO)
TREATMENT OF THROMBOCYTOPENIA
INCREASED PRODUCTION OF PLATELETS

ORAL

Cmax 255.6 NANOMOLAR

Tmax 5.5 HOUR

VD 180 LITER

PPB 96 PERCENT

Cl 6.9 LITER / HOUR

HT 19 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE AT PH 1 TO 11

THROMBOPOIETIN RECEPTOR

Thrombopoietin receptor P40238ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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