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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| AVATROMBOPAG
| AVATROMBOPAG | BLOOD | ORAL | Cmax 255.6 NANOMOLAR Tmax 5.5 HOUR VD 180 LITER PPB 96 PERCENT Cl 6.9 LITER / HOUR HT 19 HOUR SOLUBILITY PRACTICALLY INSOLUBLE AT PH 1 TO 11 | THROMBOPOIETIN RECEPTOR | Thrombopoietin receptor UNIPROT P40238 MPL more at DrugCentral | EMA | |||
