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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ERTUGLIFLOZIN
| ERTUGLIFLOZIN |
METABOLISM | ORAL | Cmax 613.7 NANOMOLAR (15 MILLIGRAM) Tmax 1 HOUR VD 85.5 LITER PPB 93.6 PERCENT Cl 11.2 LITER / HOUR HT 16.6 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | SODIUM-GLUCOSE CO-TRANSPORTER 2 (SGLT2) | Sodium,glucose cotransporter 2 UNIPROT P31639 SLC5A2 more at DrugCentral | EMA | |||
