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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| HYDROXYZINE
| HYDROXYZINE | NERVOUS SYSTEM | ORAL INJECTION | Cmax 186.9 NANOMOLAR Tmax 2 HOUR VD 1040 LITER (65 KILOGRAM) Cl 39 LITER / HOUR (65 KILOGRAM) HT 16.5 HOUR SOLUBILITY SOLUBLE IN WATER | HISTAMINE H1 RECEPTOR | Histamine H1 receptor UNIPROT P35367 HRH1 more at DrugCentral | EMA | |||
