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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GLECAPREVIR
| GLECAPREVIR | ANTIINFECTIVES | ORAL | Cmax 712.4 NANOMOLAR Tmax 5 HOUR PPB 97.5 PERCENT HT 6 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | NS3/4A PROTEASE INHIBITOR PDB 6P6T (HCV NS3,4A PROTEASE DOMAIN OF GENOTYPE 4A IN COMPLEX WITH GLECAPREVIR) LIGAND CODE = O31 (link to the list of PDB complexes) Download experimental 3D coordinates of O31 with added hydrogens | Unknown more at DrugCentral | EMA | |||
