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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LIOTHYRONINE
| LIOTHYRONINE | HORMONES | ORAL INJECTION | F 95 PERCENT HT 60 HOUR | THYROID HORMONE RECEPTOR PDB 4LNW (CRYSTAL STRUCTURE OF TR-ALPHA BOUND TO T3 IN A SECOND SITE) LIGAND CODE = T3 (link to the list of PDB complexes) Download experimental 3D coordinates of T3 with added hydrogens | Thyroid hormone receptor alpha UNIPROT P10827 THRA -- Thyroid hormone receptor beta UNIPROT P10828 THRB more at DrugCentral | EMA | |||
