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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M DEFLAZACORT (is an active metabolite)
| DEFLAZACORT | HORMONES | - | PPB 40 PERCENT | GLUCOCORTICOID RECEPTOR PDB 6W9L (STRUCTURE OF THE ANCESTRAL GLUCOCORTICOID RECEPTOR 2 LIGAND BINDING DOMAIN IN COMPLEX WITH DEACETYLATED DEFLAZACORT AND PGC1A COREGULATOR FRAGMENT) LIGAND CODE = TUS (link to the list of PDB complexes) Download experimental 3D coordinates of TUS with added hydrogens | Unknown more at DrugCentral | EMA | |||
