Cheminformatic Tools and Databases for Pharmacology

session 68679 - Total of 2 hits - Display   hits per page:

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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DEFLAZACORT (has an active metabolite)

DEFLAZACORT


ATC H02AB13

HORMONES
CORTICOSTEROID
TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY (DMD)
PRODRUG
ANTI-INFLAMMATORY
IMMUNOSUPPRESSIVE

ORAL

Tmax 1 HOUR

GLUCOCORTICOID RECEPTOR

Not determined at DrugCentralANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

2 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M DEFLAZACORT (is an active metabolite)

DEFLAZACORT


ATC H02AB13

HORMONES
CORTICOSTEROID
TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY (DMD)
PRODRUG
ANTI-INFLAMMATORY
IMMUNOSUPPRESSIVE

-

PPB 40 PERCENT

GLUCOCORTICOID RECEPTOR

PDB 6W9L (STRUCTURE OF THE ANCESTRAL GLUCOCORTICOID RECEPTOR 2 LIGAND BINDING DOMAIN IN COMPLEX WITH DEACETYLATED DEFLAZACORT AND PGC1A COREGULATOR FRAGMENT)

LIGAND CODE = TUS (link to the list of PDB complexes)

Download experimental 3D coordinates of TUS with added hydrogens

Not determined at DrugCentralANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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