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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SAFINAMIDE
| SAFINAMIDE | NERVOUS SYSTEM | ORAL | Tmax 2.5 HOUR F 95 PERCENT VD 165 LITER PPB 88 PERCENT Cl 4.6 LITER / HOUR HT 23 HOUR SOLUBILITY SOLUBLE IN WATER BUT SHOWS LOW SOLUBILITY (<0.4 MG/ML) AT PH 6.8 AND 7.5 | MONOAMINE OXIDASE TYPE B (MAO-B) | Amine oxidase flavin-containing B UNIPROT P27338 MAOB more at DrugCentral | EMA | |||
