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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LIFITEGRAST
| LIFITEGRAST | SENSORY | OPHTHALMIC | Cmax 900 PICOMOLAR SOLUBILITY SOLUBLE IN WATER | LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1 (LFA-1) | Integrin alpha-L,beta-2 UNIPROT P20701 ITGAL more at DrugCentral | EMA | |||
