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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CRISABOROLE

CRISABOROLE


ATC D11AH06

DERMATOLOGICALS
TREATMENT OF MILD TO MODERATE ATOPIC DERMATITIS
PHOSPHODIESTERASE 4 (PDE-4) INHIBITOR

TOPICAL

Cmax 506 NANOMOLAR

PPB 97 PERCENT

SOLUBILITY INSOLUBLE IN WATER

PHOSPHODIESTERASE 4

ENZYME PDE4A_HUMAN INHIBITOR P27815 PDE4B_HUMAN INHIBITOR Q07343 PDE4C_HUMAN INHIBITOR Q08493 PDE4D_HUMAN INHIBITOR Q08499ANSM (in French)

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