Cheminformatic Tools and Databases for Pharmacology

session 91399 - Total of 2 hits - Display   hits per page:

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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
URIDINE (is an active metabolite)

URIDINENATURAL MOLECULE (link)


ATC A16AX13

VARIOUS
PYRIMIDINE ANALOG
ACETYLATED PRO-DRUG OF URIDINE
EMERGENCY TREATMENT FOLLOWING A FLUOROURACIL OR CAPECITABINE OVERDOSE
CONVERTED INTO URIDINE TRIPHOSPHATE (UTP) WHICH COMPETES WITH FUTP (5-FLUOROURIDINE TRIPHOSPHATE, METABOLITE OF FLUOROURACIL) FOR INCORPORATION INTO RNA

- RNA

PDB 5M2T (X-RAY STRUCTURE OF URIDINE PHOSPHORYLASE FROM VIBRIO CHOLERAE IN COMPLEX WITH URIDINE AT 1.03 A RESOLUTION)

LIGAND CODE = URI (link to the list of PDB complexes)

Download experimental 3D coordinates of URI with added hydrogens

P2Y purinoceptor 2 UNIPROT P41231 P2RY2

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

2 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
URIDINE TRIACETATE (has an active metabolite)

URIDINE TRIACETATE


ATC A16AX13

VARIOUS
PYRIMIDINE ANALOG
ACETYLATED PRO-DRUG OF URIDINE
EMERGENCY TREATMENT FOLLOWING A FLUOROURACIL OR CAPECITABINE OVERDOSE

ORAL

Tmax 2.5 HOUR

HT 2.25 HOUR

ESTERASES

Unknown

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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