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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M SELEXIPAG (is an active metabolite)

SELEXIPAG


ATC B01AC27

BLOOD
SELECTIVE NON-PROSTANOID IP PROSTACYCLIN RECEPTOR AGONIST
TREATMENT OF PULMONARY ARTERIAL HYPERTENSION (PAH)

-

Tmax 3.5 HOUR

PPB 99 PERCENT

HT 9.8 HOUR

IP PROSTACYCLIN RECEPTOR

Prostacyclin receptor UNIPROT P43119 PTGIR

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