Cheminformatic Tools and Databases for Pharmacology

session 61045 - Total of 2 hits - Display   hits per page:

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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M SELEXIPAG (is an active metabolite)

SELEXIPAG


ATC B01AC27

BLOOD
SELECTIVE NON-PROSTANOID IP PROSTACYCLIN RECEPTOR AGONIST
TREATMENT OF PULMONARY ARTERIAL HYPERTENSION (PAH)

-

Tmax 3.5 HOUR

PPB 99 PERCENT

HT 9.8 HOUR

IP PROSTACYCLIN RECEPTOR

Prostacyclin receptor UNIPROT P43119 PTGIR

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

2 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
SELEXIPAG (has an active metabolite)

SELEXIPAG


ATC B01AC27

BLOOD
SELECTIVE NON-PROSTANOID IP PROSTACYCLIN RECEPTOR AGONIST
TREATMENT OF PULMONARY ARTERIAL HYPERTENSION (PAH)

ORAL INTRAVENOUS

Tmax 2 HOUR

PPB 99 PERCENT

Cl 35 LITER / HOUR

HT 1.65 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

IP PROSTACYCLIN RECEPTOR

Prostacyclin receptor UNIPROT P43119 PTGIR

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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