ARIPIPRAZOLE (is an active metabolite) 
| ARIPIPRAZOLE | ATC N05AX12
NERVOUS SYSTEM ANTIPSYCHOTICS TREATMENT OF BIPOLAR I DISORDER (SCHIZOPHRENIA) D2 DOPAMINE RECEPTOR AGONIST (KI=0.34 NANOMOLAR) 5HT1A AGONIST (KI=1.7 NANOMOLAR) 5HT2A ANTAGONIST (KI=3.4 NANOMOLAR) ADRENERGIC ALPHA1 RECEPTOR ANTAGONIST D3 DOPAMINE RECEPTOR PARTIAL AGONIST (KI=0.8 NANOMOLAR) | ORAL INTRAMUSCULAR | Tmax 4 HOUR F 87 PERCENT VD 404 LITER PPB 99 PERCENT Cl 3.2 LITER / HOUR (65 KILOGRAM) HT 75 HOUR | 5-HYDROXYTRYPTAMINE 1A RECEPTOR 5-HYDROXYTRYPTAMINE 2A RECEPTOR D2 DOPAMINE RECEPTOR ADRENERGIC ALPHA1 RECEPTOR PDB 6A7P (HUMAN SERUM ALBUMIN COMPLEXED WITH ARIPIPRAZOLE) LIGAND CODE = 9SC (link to the list of PDB complexes) Download experimental 3D coordinates of 9SC with added hydrogens | SEROTONIN 1A (5-HT1A) RECEPTOR PARTIAL AGONIST CHEMBL214 SEROTONIN 1A (5-HT1A) RECEPTOR P08908 5-HYDROXYTRYPTAMINE RECEPTOR 1A HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR SEROTONIN RECEPTOR | ANSM (in French) Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |
ARIPIPRAZOLE LAUROXIL (has an active metabolite) 
| ARIPIPRAZOLE LAUROXIL | ATC N05AX12
NERVOUS SYSTEM ANTIPSYCHOTICS TREATMENT OF BIPOLAR I DISORDER (SCHIZOPHRENIA) PRODRUG OF ARIPIPRAZOLE | INTRAMUSCULAR | | 5-HYDROXYTRYPTAMINE 1A RECEPTOR 5-HYDROXYTRYPTAMINE 2A RECEPTOR D2 DOPAMINE RECEPTOR ADRENERGIC ALPHA1 RECEPTOR | GPCR 5HT2A_HUMAN ANTAGONIST P28223 5HT1A_HUMAN PARTIAL AGONIST P08908 DRD2_HUMAN PARTIAL AGONIST P14416 | ANSM (in French) Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |