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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FLIBANSERIN
| FLIBANSERIN | NERVOUS SYSTEM | ORAL | Cmax 1.07 MICROMOLAR Tmax .075 HOUR F 33 PERCENT PPB 98 PERCENT HT 11 HOUR SOLUBILITY INSOLUBLE IN WATER | 5-HT1A RECEPTOR 5-HT2A RECEPTOR | 5-hydroxytryptamine receptor 1A UNIPROT P08908 HTR1A -- 5-hydroxytryptamine receptor 2A UNIPROT P28223 HTR2A more at DrugCentral | EMA | |||
