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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SACUBITRIL (has an active metabolite)
| SACUBITRIL | CARDIOVASCULAR | ORAL | Tmax 0.5 HOUR F 60 PERCENT VD 103 LITER PPB 94 PERCENT Cl 51 LITER / HOUR (EQN) HT 1.4 HOUR | NEPRILYSIN | Neprilysin UNIPROT P08473 MME more at DrugCentral | EMA | |||
