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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DACLATASVIR DISCONTINUED
| DACLATASVIR |
ANTIINFECTIVES | ORAL | Tmax 2 HOUR F 67 PERCENT VD 47 LITER PPB 99 PERCENT Cl 4.2 LITER / HOUR HT 13.5 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | NS5A | GENOME POLYPROTEIN POLG_HCVH INHIBITOR P27958 POLG_HCVBK INHIBITOR P26663 | ANSM (in French) | |||
