Cheminformatic Tools and Databases for Pharmacology

session 25920 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
SONIDEGIB

SONIDEGIB


ATC L01XX48

ANTINEOPLASTIC
SMOOTHENED (SMO) ANTAGONIST WHICH INHIBITS THE HEDGEHOG (HH) SIGNALING PATHWAY

ORAL

Cmax 2.12 MICROMOLAR (200 MG ONCE DAILY)

Tmax 3 HOUR

F 10 PERCENT

VD 9166 LITER

PPB 97 PERCENT

Cl 9.4 LITER / HOUR (EQN)

HT 672 HOUR

SOLUBILITY INSOLUBLE IN WATER

SMOOTHENED (SMO)

GPCR SMO_HUMAN ANTAGONIST Q99835ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |