| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SONIDEGIB
| SONIDEGIB | ANTINEOPLASTIC | ORAL | Cmax 2.12 MICROMOLAR (200 MG ONCE DAILY) Tmax 3 HOUR F 10 PERCENT VD 9166 LITER PPB 97 PERCENT Cl 9.4 LITER / HOUR (EQN) HT 672 HOUR SOLUBILITY INSOLUBLE IN WATER | SMOOTHENED (SMO) | Smoothened homolog UNIPROT Q99835 SMO more at DrugCentral | EMA | |||
