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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| HYDROXYAMPHETAMINE DISCONTINUED (is an active metabolite)
| HYDROXYAMPHETAMINE | NERVOUS SYSTEM | OPHTHALMIC | MONOAMINE TRANSPORTER PDB 3BUF (BACE-1 COMPLEXED WITH COMPOUND 2) LIGAND CODE = AEG (link to the list of PDB complexes) Download experimental 3D coordinates of AEG with added hydrogens | Sodium-dependent noradrenaline transporter UNIPROT P23975 SLC6A2 -- Sodium-dependent dopamine transporter UNIPROT Q01959 SLC6A3 more at DrugCentral | EMA | ||||
