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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CLOFIBRATE DISCONTINUED (has an active metabolite)
| CLOFIBRATE | CARDIOVASCULAR | ORAL | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA AGONIST CHEMBL239 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA Q07869 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR1 NR1C NR1C1 | ANSM (in French) | ||||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M CLOFIBRATE (is an active metabolite)
| CLOFIBRATE | CARDIOVASCULAR | - | Cmax 932.8 MICROMOLAR PPB 96 PERCENT HT 20 HOUR | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA AGONIST CHEMBL239 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA Q07869 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR1 NR1C NR1C1 | ANSM (in French) | |||
