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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M DOXEPIN (is an active metabolite)
| DOXEPIN | NERVOUS SYSTEM | - | HT 31 HOUR | HISTAMINE H2 RECEPTOR HISTAMINE H1 RECEPTOR | Sodium-dependent noradrenaline transporter UNIPROT P23975 SLC6A2 -- Histamine H1 receptor UNIPROT P35367 HRH1 more at DrugCentral | EMA | |||
