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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
EDOXABAN

EDOXABAN


ATC B01AF03

CARDIOVASCULAR
FACTOR XA INHIBITOR
TO REDUCE THE RISK OF STROKE AND SYSTEMIC EMBOLISM
TREATMENT OF DEEP VEIN THROMBOSIS AND PULMONARY EMBOLISM

ORAL

Tmax 1.5 HOUR

F 62 PERCENT

VD 107 LITER

PPB 55 PERCENT

Cl 22 LITER / HOUR

HT 12 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE AT PH 6-7

FACTOR XA

COAGULATION FACTOR X INHIBITOR CHEMBL244 COAGULATION FACTOR X P00742 COAGULATION FACTOR X HOMO SAPIENS ENZYME PROTEASE SERINE PAS S1AANSM (in French)

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