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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
MILTEFOSINE

MILTEFOSINE


ATC L01XX09
ATC P01CX04

ANTIPARASITIC
ANTINEOPLASTIC
TREATMENT OF LEISHMANIASIS
INTERACTION WITH LIPIDS (PHOSPHOLIPIDS AND STEROLS)
INHIBITION OF CYTOCHROME C OXIDASE
APOPTOSIS-LIKE CELL DEATH

ORAL

Cmax 162.2 MICROMOLAR

Tmax 7 HOUR

PPB 98 PERCENT

HT 153.6 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

MEMBRANE

RAC-alpha serine/threonine-protein kinase P31749 (AKT1_HUMAN)ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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