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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NALOXEGOL
| NALOXEGOL | METABOLISM | ORAL | Tmax 2 HOUR VD 1554 LITER PPB 4.2 PERCENT Cl 126 LITER / HOUR (EQN) HT 8.5 HOUR SOLUBILITY HIGH AQUEOUS SOLUBILITY ACROSS THE PHYSIOLOGIC PH RANGE | MU-OPIOID RECEPTOR | Mu-type opioid receptor UNIPROT P35372 OPRM1 more at DrugCentral | EMA | |||
