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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CEFTOLOZANE

CEFTOLOZANE


ATC J01DI54

ANTIINFECTIVES
CEPHALOSPORIN ANTIBACTERIAL DRUG FOR PARENTERAL ADMINISTRATION
PENICILLIN-BINDING PROTEINS (PBPS) INHIBITOR

INTRAVENOUS

Cmax 111.5 MICROMOLAR

Tmax 1.07 HOUR

VD 13.5 LITER

PPB 18.5 PERCENT

Cl 5.4 LITER / HOUR

HT 3.12 HOUR

PENICILLIN-BINDING PROTEINS (PBPS)

Unknown

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