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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PERAMIVIR
| PERAMIVIR | ANTIINFECTIVES | INTRAVENOUS | Cmax 142.6 MICROMOLAR Tmax 0.5 HOUR VD 12.5 LITER PPB 30 PERCENT Cl 0.43 LITER / HOUR (EQN) HT 20 HOUR | NEURAMINIDASE PDB 3K39 (CRYSTAL STRUCTURE OF B, PERTH NEURAMINIDASE D197E MUTANT IN COMPLEX WITH PERAMIVIR) LIGAND CODE = BCZ (link to the list of PDB complexes) Download experimental 3D coordinates of BCZ with added hydrogens | Neuraminidase UNIPROT P03468 -- Neuraminidase UNIPROT P03474 more at DrugCentral | EMA | |||
