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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DROXIDOPA (has an active metabolite)

DROXIDOPA


ATC C01CA27

CARDIOVASCULAR
TREATMENT OF ORTHOSTATIC DIZZINESS AND LIGHTHEADEDNESS
SYNTHETIC AMINO ACID PRECURSOR OF NOREPINEPHRINE
SUBSTRATE OF DOPA-DECARBOXYLASE

ORAL

Tmax 2 HOUR

VD 200 LITER

PPB 75 PERCENT

Cl 55.4 LITER / HOUR (EQN)

HT 2.5 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

DOPA-DECARBOXYLASE

ADRENERGIC RECEPTOR AGONIST CHEMBL2331074 ADRENERGIC RECEPTOR P07550 BETA-2 ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTORANSM (in French)

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BindingDB
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