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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
EMPAGLIFLOZIN

EMPAGLIFLOZIN


ATC A10BX12
ATC A10BD19
ATC A10BK03
ATC A10BD20

METABOLISM
TREATMENT OF TYPE 2 DIABETES MELLITUS
SODIUM-GLUCOSE CO-TRANSPORTER2 (SGLT2) INHIBITOR

ORAL

Cmax 687 NANOMOLAR

Tmax 1.5 HOUR

VD 73.8 LITER

PPB 86.2 PERCENT

Cl 10.6 LITER / HOUR

HT 12.4 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER

SODIUM-GLUCOSE CO-TRANSPORTER2 (SGLT2)

SODIUM/GLUCOSE COTRANSPORTER 2 INHIBITOR CHEMBL3884 SODIUM/GLUCOSE COTRANSPORTER 2 P31639 SODIUM/GLUCOSE COTRANSPORTER 2 HOMO SAPIENS TRANSPORTER ELECTROCHEMICAL SLC SLC05ANSM (in French)

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