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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DYCLONINE
| DYCLONINE | NERVOUS SYSTEM | TOPICAL | PDB 7UGG (CRYO-EM STRUCTURE OF TRPV3 IN COMPLEX WITH THE ANESTHETIC DYCLONINE) LIGAND CODE = N8R (link to the list of PDB complexes) Download experimental 3D coordinates of N8R with added hydrogens | Sodium channel protein type 10 subunit alpha UNIPROT Q9Y5Y9 SCN10A more at DrugCentral | EMA | ||||
