| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M LOSARTAN (is an active metabolite)
| LOSARTAN |
CARDIOVASCULAR | - | Tmax 3.5 HOUR VD 12 LITER PPB 99.8 PERCENT Cl 3 LITER / HOUR HT 7.5 HOUR | TYPE-1 ANGIOTENSIN II RECEPTOR | Type-1 angiotensin II receptor UNIPROT P30556 AGTR1 more at DrugCentral | EMA | |||
