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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PREDNISONE

PREDNISONE


ATC A07EA03
ATC H02AB07

METABOLISM
GLUCOCORTICOID
ANTI-INFLAMMATORY AGENTS
ANTINEOPLASTIC AGENTS
ADRENOCORTICAL STEROIDS

ORAL

Cmax 801 NANOMOLAR (PMID21982386)

Tmax 2.2 HOUR

VD 37 LITER (65 KILOGRAM)

PPB 73 PERCENT

Cl 11 LITER / HOUR

HT 2.6 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER

GLUCOCORTICOID RECEPTOR

GLUCOCORTICOID RECEPTOR AGONIST CHEMBL2034 GLUCOCORTICOID RECEPTOR P04150 GLUCOCORTICOID RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3C NR3C1ANSM (in French)

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