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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M RIFAPENTINE (is an active metabolite)
| RIFAPENTINE | ANTIINFECTIVES | - | Cmax 7.5 MICROMOLAR Tmax 11.2 HOUR PPB 93.2 PERCENT HT 13 HOUR | DNA-DIRECTED RNA POLYMERASE | Bacterial DNA-directed RNA polymerase UNIPROT P0A7Z4 rpoA more at DrugCentral | EMA | |||
