Cheminformatic Tools and Databases for Pharmacology

session 99575 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CYCLOGUANIL (is an active metabolite)

CYCLOGUANIL


ATC P01BB52
ATC P01BB01
ATC P01BB51

ANTIPARASITIC
ANTIMALARIAL
ANTIMETABOLITES
DIHYDROFOLATE REDUCTASE INHIBITOR

-

Tmax 5 HOUR

HT 19 HOUR

DIHYDROFOLATE REDUCTASE

PDB 3UM8 (WILD-TYPE PLASMODIUM FALCIPARUM DHFR-TS COMPLEXED WITH CYCLOGUANIL AND NADPH)

LIGAND CODE = 1CY (link to the list of PDB complexes)

Download experimental 3D coordinates of 1CY with added hydrogens

Bifunctional dihydrofolate reductase-thymidylate synthase UNIPROT P13922

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |