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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M TRAVOPROST (is an active metabolite)
| TRAVOPROST | SENSORY | - | Cmax 0.04 NANOMOLAR Tmax 0.5 HOUR HT 0.75 HOUR | FP PROSTANOID RECEPTOR | Prostaglandin F2-alpha receptor UNIPROT P43088 PTGFR more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TRAVOPROST (has an active metabolite)
| TRAVOPROST | SENSORY | OPHTHALMIC | SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | FP PROSTANOID RECEPTOR | Prostaglandin F2-alpha receptor UNIPROT P43088 PTGFR more at DrugCentral | EMA | |||
