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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
OLMESARTAN (is an active metabolite)

OLMESARTAN


ATC C09CA08
ATC C09DB02
ATC C09DA08
ATC C09DX03

CARDIOVASCULAR
SELECTIVE AT1 SUBTYPE ANGIOTENSIN II RECEPTOR INHIBITOR PRODRUG
ANTIHYPERTENSIVE
TREATMENT OF HYPERTENSION

-

Tmax 1.5 HOUR

F 26 PERCENT

VD 17 LITER

PPB 99 PERCENT

Cl 1.3 LITER / HOUR

HT 13 HOUR

TYPE-1 ANGIOTENSIN II RECEPTOR

Type-1 angiotensin II receptor P30556 (AGTR1_HUMAN)ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

2 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
OLMESARTAN MEDOXOMIL (has an active metabolite)

OLMESARTAN MEDOXOMIL


ATC C09CA08
ATC C09DB02
ATC C09DA08
ATC C09DX03

CARDIOVASCULAR
SELECTIVE AT1 SUBTYPE ANGIOTENSIN II RECEPTOR INHIBITOR PRODRUG
ANTIHYPERTENSIVE
TREATMENT OF HYPERTENSION

ORAL

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

TYPE-1 ANGIOTENSIN II RECEPTOR

Type-1 angiotensin II receptor P30556 (AGTR1_HUMAN)ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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