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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M GANCICLOVIR (is an active metabolite)

GANCICLOVIR


ATC J05AB06
ATC S01AD09

ANTIINFECTIVES
ANTIVIRAL
CYTOMEGALOVIRUS (CMV)
HERPES SIMPLEX VIRUS (HSV)
COMPETITIVE INHIBITION OF VIRAL DNA POLYMERASES
INCORPORATION INTO VIRAL DNA RESULTING IN EVENTUAL TERMINATION OF VIRAL DNA ELONGATION
NUCLEOSIDE ANALOGUE

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HUMAN HERPESVIRUS 1 DNA POLYMERASE INHIBITOR CHEMBL1872 HUMAN HERPESVIRUS 1 DNA POLYMERASE P04293 DNA POLYMERASE CATALYTIC SUBUNIT HERPES SIMPLEX VIRUS (TYPE 1 / STRAIN 17) ENZYME TRANSFERASEANSM (in French)

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