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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M GANCICLOVIR (is an active metabolite)
| GANCICLOVIR | ANTIINFECTIVES | - | PDB 7AOM (STRUCTURE OF NUDT15 IN COMPLEX WITH GANCICLOVIR TRIPHOSPHATE) LIGAND CODE = RQ2 (link to the list of PDB complexes) Download experimental 3D coordinates of RQ2 with added hydrogens | DNA polymerase catalytic subunit UNIPROT P04293 more at DrugCentral | EMA | ||||
