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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M CLOFARABINE (is an active metabolite)
| CLOFARABINE | ANTINEOPLASTIC | - | RIBONUCLEOTIDE REDUCTASE | DNA polymerase alpha catalytic subunit UNIPROT P09884 POLA1 -- Ribonucleoside-diphosphate reductase large subunit UNIPROT P23921 RRM1 more at DrugCentral | EMA | ||||
