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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MEPROBAMATE (is an active metabolite)
| MEPROBAMATE |
NERVOUS SYSTEM | ORAL | Cmax 11.4 MICROMOLAR Tmax 4.5 HOUR VD 45.5 LITER (65 KILOGRAM) PPB 0 PERCENT Cl 2.34 LITER / HOUR (65 KILOGRAM) HT 9.6 HOUR | GAMMA-AMINOBUTYRIC-ACID RECEPTOR (GABA) (PMID9067327) | GABA-A receptor alpha-2,beta-3,gamma-2 UNIPROT P18507 GABRG2 -- GABA-A receptor alpha-3,beta-3,gamma-2 UNIPROT P18507 GABRG2 more at DrugCentral | EMA | |||
