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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
POLIDOCANOL

POLIDOCANOL


ATC C05BB02

CARDIOVASCULAR
SCLEROSING AGENTS FOR LOCAL INJECTION
ANTIVARICOSE THERAPY
DAMAGING EFFECT ON THE ENDOTHELIUM OF BLOOD VESSELS
ATTACHES TO THE LIPID CELL MEMBRANE OF THE VENOUS ENDOTHELIUM, RESULTING IN DISRUPTION OF THE OSMOTIC BARRIER, DESTRUCTION OF THE VENOUS ENDOTHELIUM, AND VASOSPASM

 INTRAVENOUS

VD 58.5 LITER

Cl 18 LITER / HOUR

HT 2.1 HOUR

SOLUBILITY SOLUBLE IN WATER

 MEMBRANE

 Unknown

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