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INN

Class

Route (list)

PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used

Primary Target and PDB code of Protein-Drug complex

Targets from DrugCentral

Links

POLIDOCANOL

ATC C05BB02

CARDIOVASCULAR
SCLEROSING AGENTS FOR LOCAL INJECTION
ANTIVARICOSE THERAPY
DAMAGING EFFECT ON THE ENDOTHELIUM OF BLOOD VESSELS
ATTACHES TO THE LIPID CELL MEMBRANE OF THE VENOUS ENDOTHELIUM, RESULTING IN DISRUPTION OF THE OSMOTIC BARRIER, DESTRUCTION OF THE VENOUS ENDOTHELIUM, AND VASOSPASM

INTRAVENOUS

VD 58.5 LITER

Cl 18 LITER / HOUR

HT 2.1 HOUR

SOLUBILITY SOLUBLE IN WATER

MEMBRANE

Unknown

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

VigiAccess
SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank