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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
LULICONAZOLE

LULICONAZOLE


ATC D01AC18

ANTIINFECTIVES
AZOLE ANTIFUNGAL
TOPICAL TREATMENT OF INTERDIGITAL TINEA PEDIS, TINEA CRURIS, AND TINEA CORPORIS CAUSED BY THE ORGANISMS TRICHOPHYTON RUBRUM AND EPIDERMOPHYTON FLOCCOSUM
APPEARS TO INHIBIT ERGOSTEROL SYNTHESIS (CONSTITUENT OF FUNGAL CELL MEMBRANES) BY INHIBITING THE ENZYME LANOSTEROL DEMETHYLASE

TOPICAL

Cmax 20.8 NANOMOLAR

PPB 99 PERCENT

LANOSTEROL DEMETHYLASE

Lanosterol 14-alpha demethylase UNIPROT P10613 ERG11

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