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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
UMECLIDINIUM

UMECLIDINIUM


ATC R03AL03
ATC R03BB07

RESPIRATORY
ANTICHOLINERGIC
ANTIMUSCARINIC AGENT
MUSCARINIC RECEPTORS ANTAGONISTS
INDICATED FOR THE LONG-TERM, ONCE-DAILY, MAINTENANCE TREATMENT OF AIRFLOW OBSTRUCTION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

INHALATION

VD 86 LITER

PPB 89 PERCENT

Cl 5.4 LITER / HOUR (EQN)

HT 11 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

MUSCARINIC RECEPTORS M1 TO M5

MUSCARINIC ACETYLCHOLINE RECEPTOR M3 ANTAGONIST CHEMBL245 MUSCARINIC ACETYLCHOLINE RECEPTOR M3 P20309 MUSCARINIC ACETYLCHOLINE RECEPTOR M3 HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ACETYLCHOLINE RECEPTORANSM (in French)

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