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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
UMECLIDINIUM

UMECLIDINIUM


ATC R03AL03

RESPIRATORY
ANTICHOLINERGIC
ANTIMUSCARINIC AGENT
MUSCARINIC RECEPTORS ANTAGONISTS
INDICATED FOR THE LONG-TERM, ONCE-DAILY, MAINTENANCE TREATMENT OF AIRFLOW OBSTRUCTION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

INHALATION

VD 86 LITER

PPB 89 PERCENT

Cl 5.4 LITER / HOUR (EQN)

HT 11 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

MUSCARINIC RECEPTORS M1 TO M5

Muscarinic acetylcholine receptor M3 UNIPROT P20309 CHRM3

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