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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CANAGLIFLOZIN

CANAGLIFLOZIN


ATC A10BX11
ATC A10BK02
ATC A10BD16

METABOLISM
TYPE 2 DIABETES MELLITUS
SODIUM-GLUCOSE CO-TRANSPORTER 2 INHIBITOR

ORAL

F 65 PERCENT

VD 119 LITER

PPB 99 PERCENT

Cl 11.5 LITER / HOUR

HT 13.1 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER FROM PH 1.1 TO 12.9

SODIUM-GLUCOSE CO-TRANSPORTER 2 (SGLT2)

SODIUM/GLUCOSE COTRANSPORTER 2 INHIBITOR CHEMBL3884 SODIUM/GLUCOSE COTRANSPORTER 2 P31639 SODIUM/GLUCOSE COTRANSPORTER 2 HOMO SAPIENS TRANSPORTER ELECTROCHEMICAL SLC SLC05ANSM (in French)

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