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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
OSPEMIFENE

OSPEMIFENE


ATC G03XC05

DYSPAREUNIA MENOPAUSE
ESTROGEN AGONIST/ANTAGONIST

ORAL

Cmax 3.16 MICROMOLAR

VD 448 LITER

PPB 99 PERCENT

Cl 9.16 LITER / HOUR

HT 26 HOUR

SOLUBILITY INSOLUBLE IN WATER

ESTROGEN RECEPTOR

ESTROGEN RECEPTOR MODULATOR CHEMBL2093866 ESTROGEN RECEPTOR P03372 ESTROGEN RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3A NR3A1ANSM (in French)

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